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Methylprednisolone “pulse” therapy was performed on 22 patients of childhood nephropathies who
showed resistance to conventional therapy. The diseases included steroid-resistant or frequent relaps-
ing nephrotic syndrome including minimal change nephrotic syndrome, focal segmental glomer-
ulosclerosis, membranous nephropathy, mesangioproliferative glomerulonephritis, Henoch-Schonlein
purpura nephritis and SLE nephritis. Methylprednisolone 30 mg/kg/day was administered
intravenously over one hour, which was repeated 6 times on every other day.
Sixteen of... |
